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Title: The Effects of Chia Seeds Consumption on HbA1c, Insulin Level, Lipid Profile, and C-Reactive-Protein in People with Type 2 Diabetes
Authors: Eman Zaid Al-Wases 
Supervisor: Dr. Tasleem A. Zafar
Keywords: Type 2 Diabetes : Inflammation
Issue Date: 2017
Publisher:  Kuwait university - college of graduate studies
Abstract: The prevalence rates of obesity and Type-2-diabetes (T2DM) have reached epidemic levels worldwide, and in Kuwait, the population is highly affected. Dietary modification remains a cornerstone in the management of obesity and T2DM. Health professionals are exploring functional foods for their therapeutic use for glycemic control and to decrease the risk of T2DM related health complications. Dietary fibers and long-chain polyunsaturated fatty acids (PUFA) have shown benefits in controlling blood glucose concentration, enhancing insulin sensitivity, lowering high blood pressure, and other cardiovascular disease risk factors. We investigated Chia seed (Salvia hispanica L), an excellent source of dietary fiber and omega-3 α-linolenic acid (ALA), for its effect on fasting blood glucose (FBG), insulin level, HbA1c, blood pressure, lipid- profile and inflammatory marker (hs-CRP) in a group of T2DM patients. We divided forty four volunteers were into two groups. Group 1, intervention group (n = 20) was supplied chia seeds to consume as 40 g/day added to any food or drink for 12 weeks; Group 2, the control group (n=24) did not consume any supplement for the study duration. Blood samples were collected at the beginning and end of the intervention period to assess for the difference in glycemic control and cardiovascular risk parameters. Anthropometric and blood pressure data were also collected at baseline and after the intervention. The results showed a significant reduction in systolic blood pressure in the intervention group compared to baseline level mean difference (-13.65 ± 16.3, P=0.001) with no change in the control systolic blood pressure (1.66 ± 13.1, P=0.354). There were no significant changes found in any of the glycemic parameters, body weight measures and the inflammatory markers hs-CRP in both groups. In conclusion, consumption of 40 g chia seeds for 12 weeks decreased high systolic blood pressure significantly with no significant effects on the glycemic and other cardiovascular parameters in people with Type 2 diabetes
Appears in Programs:1820 Nutrition Science & Food Science

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